![]() ![]() The inhaled antigens produce a hypersensitivity immune reaction causing inflammation of the airspaces ( alveoli) and small airways ( bronchioles) within the lung. ![]() People affected by this type of lung inflammation ( pneumonitis) are commonly exposed to the antigens by their occupations, hobbies, the environment and animals. Common antigens include molds, bacteria, bird droppings, bird feathers, agricultural dusts, bioaerosols and chemicals from paints or plastics. Hypersensitivity pneumonitis ( HP) or extrinsic allergic alveolitis ( EAA) is a syndrome caused by the repetitive inhalation of antigens from the environment in susceptible or sensitized people. Idiopathic Pulmonary Fibrosis, Occupational asthma, SarcoidosisĪvoidance of antigen exposure and sometimes steroids Variety of respirable antigens found in farming, food processing, handing of animals, and different occupational settingsīased on home and environmental exposure history taking followed by imaging, spirometry, serology, bronchoscopy, and even lung biopsy. Hours to years depending on type of exposure.Īcute, Subacute, Chronic or Fibrotic vs. Pulmonology, Occupational Safety and Health, Occupational Medicine, Immunologyĭyspnea, fever, chills, cough, fatigue, weight loss A multinucleated giant cell, seen within the walls of the air sacs to the right of the picture halfway down, is an important clue to the correct diagnosis. High magnification photomicrograph of a lung biopsy taken showing chronic hypersensitivity pneumonitis ( H&E), showing mild thickening of the walls of the small air sacs by invasion of white blood cells. Medical condition Hypersensitivity PneumonitisĪllergic alveolitis, bagpipe lung, extrinsic allergic alveolitis (EAA) ![]()
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